Buschke Löwenstein Tumor of the Right Lower Abdominal Wall: Case Report and Review of the Literature
- Authors
-
-
Martin Balog
Klinik für Allgemein-und Viszeralchirurgie, Thoraxchirurgie und Proktologie des Klinikums Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany -
Ulrich Lang
Institut für Pathologie, Klinikum Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany -
Günther Winde
Klinik für Allgemein-und Viszeralchirurgie, Thoraxchirurgie und Proktologie des Klinikums Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany
-
- Keywords:
- Buschke-Löwenstein tumor, Giant condyloma acuminatum, surgical resection, neoadjuvant therapy, squamous cell carcinoma
- Abstract
-
Buschke-Löwenstein tumor (BLT), known as giant condyloma acuminatum (GCA), is a very rare disease that typically appears as a penile lesion but can although appear in the anogenital region, bladder, vulva, scrotum and sacrococcygeal area as well. Despite of its histologically benign signs, a high recurrence rate, invasiveness and destructive growth characterizes this rare disease as clinically malignant. Malignant transformation into verrucous carcinoma (VC) and squamous-cell carcinoma (SCC) have been described as well. Many treatment modalities inclusive neoadjuvant radio-and chemotherapy and topical treatment have been reported but due to lack of controlled studies no treatment can be recommended. We present a case of Buschke-Löwenstein tumor involving the right lower abdominal wall of the colostomy region at a 71 years old male. To our knowledge, we first describe a case report of GCA involving abdominal wall at the colostomy region, successfully treated by wide radical excision and plastic reconstruction.
- References
-
Buschke A, Löwenstein L. Über karzinomähnlich Condylomata acuminata des Penis. KlinWochenschr 1925; 4: 1726-1728. http://dx.doi.org/10.1007/BF01728480
Dawson DF, Duckworth SK, Bernhardt H, Young JM. Giant condyloma and verrucous carcinoma of he genital area. Arch Pathol 1965; 79: 225-231.
Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ. Giant condyloma accuminatum ( Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon Rectum 1994; 37(9): 950-957. http://dx.doi.org/10.1007/BF02052606
Creasman C, Haas PA, Fox TA Jr, Balasz M. Malignant transformation of anorectal giant condyloma accuminatum (Buschke-Löwenstein Tumor). Dis Colon Rectum 1989; 32: 481-487. http://dx.doi.org/10.1007/BF02554502
Trombetta U, Place RJ. Giant condyloma acuminatum of the anorectum: trends in epidemiology and managemnet. Dis Colon Rectum 2001; 44: 1878-1886. http://dx.doi.org/10.1007/BF02234473
Yakan S, Cengiz F, Telciler KE, Zu M, Denecli AG. Rectal involvement of reccurent Buschke-Lowenstein Tumor causing subileus: a case report. Gastroenterology Research 2001; 4(4): 177-179.
Norris CS. Giant condyloma acuminatum (Buschke-Lowenstein tumor) involving a pilonidal sinus: a case report and review of a literature. J Surg Oncol 1983; 22(1): 47-50. http://dx.doi.org/10.1002/jso.2930220113
Wiedemann A, Diekmann WP, Holtmann G, Kracht H. Report of a case with giant condyloma (Buschke-Löwenstein tumor) localized in the bladder. J Urol 1995; 153(4): 1222-4. http://dx.doi.org/10.1016/S0022-5347(01)67559-1
Rhea WG Jr, Bourgeois BM, Sewell DR. Condyloma acuminata: a fatal disease? Am.Surg 1998; 64(11): 1082-7.
Mentes O, Akbulut M, Bagci M. Verrucous carcinoma (Buschke –Lowenstein) arising in a sacrococcygeal pilonidal sinus tract: report of a case. Langenbecks Arch Surg 2008; 393(1): 111-4. http://dx.doi.org/10.1007/s00423-007-0209-y
Piepkorn M, Kumasaka B, Krieger JN, Burmer GC. Development of human papillomavirus-associated Buschke-Löwenstein penile carcinoma during cyclosporine therapy for generalized pustular psoriasis. J Am Acad Dermatol 1993; 29(2 Pt 2): 321-5. http://dx.doi.org/10.1016/0190-9622(93)70186-W
Renzi A, Brusciano L, Giordano P, Rosseti G, Izzo D, Del Genio A. Buschke Lowenstein Tumor successful treatment by surgical excision alone: a case report. Chir Ital 2004; 56: 297-300.
Chao MWT, Gibbs P. Squamous cell carcinoma arising in a giant accuminatum (Buschke-Löwenstein tumor). Asian J Surg 2005; 28: 238-240. http://dx.doi.org/10.1016/S1015-9584(09)60352-3
Pacha O, Pickett MM, Hebert AA. Scrotal Buscke-Lowenstein tumor in an AIDS Patient Sex.Transm Dis 2012; 39(3): 236-7. http://dx.doi.org/10.1097/OLQ.0b013e318244ac66
Mstrangelo M, Mobiglia A, Cassoni P, Castellano I, Maass J, Martina MC, Bello M, Mussa A. Verrucous carcinoma of the anus or Buschke-Lowenstein tumor of the anus: staging and treatment.Report of 3 cases. Suppl Tumori 2005; May-Jun; 4(3): S29-30.
Wietfeldt ED, Thiele J. Malignancies of the anal margin and perianal skin. Clin Colon Rectal Surg 2009; 22: 127-135. http://dx.doi.org/10.1055/s-0029-1223845
Prasad ML, Abcarian H. Malignant potential of perianal condyloma acuminatum. Dis Colon Rectum 1980; 23: 191-7. http://dx.doi.org/10.1007/BF02587626
Abcarian H, Smith D, Sharon N. The immunotherapy of anal condyloma acuminatum. Dis Colon Rectum 1976; 19: 237-244. http://dx.doi.org/10.1007/BF02590909
Efthaiha MS, Amshel Al, Shonberg IL, Batshon B. Giant and reccurent condyloma acuminatum appraisla of immunotherapy. Dis Colon Rectum 1982; 25: 136-138. http://dx.doi.org/10.1007/BF02553258
Hyacinthe M, Karl R, Coppola D, Goodgame T, Redwood W, Goldenfarb P, Ohori NP, Marcet J. Squamous cell carcinoma of pelvis in a giant condyloma acuminatum: use of neoadjuvant chemoradiation and surgical rsection: report of a case. Dis Colon Rectum 1998; 41: 1450-1453. http://dx.doi.org/10.1007/BF02237065
Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J. Combined surgery and chemoradiation as a treatment for the Buschke-Lowenstein tumour. Surgeon 2006; 4: 378-383. http://dx.doi.org/10.1016/S1479-666X(06)80114-9
Yoshimura Y, Mishima K, Obara S, Nariai Y, Yoshimura H, Mikami T. Treatment modalities for oral verrucous carcinomas and their outcomes: contribution of radiotherapy and chemotherapy. Int J Clin Oncol 2001; 6: 192-200. http://dx.doi.org/10.1007/PL00012104
Schwade JG, Wara WM, Dedo HH, Phillips TL. Radiotherapy for verrucous carcinoma. Radiology 1976; 120: 677-679. http://dx.doi.org/10.1148/120.3.677
Sobrado CW, Mester N, Nadalin W, Nahas SC, Bocchini SF, Habr-Gama A . Radiation-induced total regression of a highly recurrent giant perianal condyloma: report of a case. Dis Colon Rectum 2000; 43: 257-260. http://dx.doi.org/10.1007/BF02236991
Schwartz RA. Verrucous carcinoma of the skin and mucosa.J Am Acad Dermatolo 1995; 32: 1-21. http://dx.doi.org/10.1016/0190-9622(95)90177-9
Bertram P, Treutner KH, Rübben A, Hauptmann S, Schumpelick V. Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Löwenstein tumor). Langenbecks Arch Chir 1995; 380(2): 115-8. http://dx.doi.org/10.1007/BF00186418
- Downloads
- Published
- 2015-01-09
- Issue
- Vol. 4 No. 1 (2015)
- Section
- Articles
How to Cite
Similar Articles
- Maria Caffo, Lucia Merlo, Valeria Barresi, Ema Tot, Gerardo Caruso, Brain Metastases: State of the Art and Innovative Targeted Therapies , Journal of Analytical Oncology: Vol. 4 No. 3 (2015)
- Radu Radulescu, Alexandra Totan, Bogdan Calenic, Cosmin Totan , Maria Greabu, Biomarkers of Oxidative Stress, Proliferation, Inflammation and Invasivity in Saliva from Oral Cancer Patients , Journal of Analytical Oncology: Vol. 4 No. 1 (2015)
- Tommaso Cai, Gabriella Nesi, Sandra Mazzoli, Francesca Meacci, Galliano Tinacci, Cesare Selli , Riccardo Bartoletti , Inflammation and Urothelial Bladder Cancer: What we Need to Known? (Review) , Journal of Analytical Oncology: Vol. 4 No. 2 (2015)
- Juan Pablo Nicola, Ana María Masini-Repiso, Emerging Therapeutics for Radioiodide-Refractory Thyroid Cancer , Journal of Analytical Oncology: Vol. 5 No. 2 (2016)
- Martin Balog, Ulrich Lang , Günther Winde , Solitary Extramedullary Plasmocytoma of the Thyroid Gland: A Case Report , Journal of Analytical Oncology: Vol. 4 No. 1 (2015)
- Mervat Mahrous, Tasabeeh Mohamed, Ghassan Al SISI, Ahmed Al-Hujaily, Samira AlSumani, Primary Squamous Cell Carcinoma of the Breast is a Rare and Special Entity , Journal of Analytical Oncology: Vol. 7 No. 3 (2018)
- D.A. Tzerkovsky, A.N. Mazurenko, F.F. Borychevsky, D.V. Shashkouski, Radiodynamic Therapy with Photosensitizers: Mini-Review of Experimental and Clinical Studies , Journal of Analytical Oncology: Vol. 11 (2022)
- T.G. Shrihari, Chronic Inflammatory Mediators Induced Malignant Changes in Inflammatory Microenvironment of Oral Potentialy Malignant Conditions - An Emerging Concept , Journal of Analytical Oncology: Vol. 7 No. 4 (2018)
- Megha Jain, Vipin Jain, Anish Gupta, Swati Saawarn, Samar Khan, Role of Hormones in Oral Squamous Cell Carcinoma - An Update , Journal of Analytical Oncology: Vol. 6 No. 4 (2017)
- Kouichi Nonaka, Ryosuke Gushima, Kouichi Sakurai, Hiroto Kita, Yutaka Sasaki, Endoscopic Submucosal Dissection for Superficial Esophageal Neoplasms , Journal of Analytical Oncology: Vol. 1 No. 1 (2012)
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Martin Balog, Ulrich Lang , Günther Winde , Solitary Extramedullary Plasmocytoma of the Thyroid Gland: A Case Report , Journal of Analytical Oncology: Vol. 4 No. 1 (2015)