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E-Survey: Current Status of Proton Beam Therapy in USA

Authors

  • A. Taqaddas

    Research Medical Physicist, Research Wormhole, Canada; Certified International project manager Member of APS and ASCO USA Member of ESTRO, Europe

DOI:

https://doi.org/10.30683/1927-7229.2021.10.05

Keywords:

Cancer, Proton Beam Therapy, Intensity modulated Proton Therapy, Single field uniform scanning, Quality Assurance, Synchrotron

Abstract

The clinical use of Proton Beam Therapy (PBT) in the management of cancer is increasing worldwide. USA has high number of proton therapy centres and this number is growing with new proton therapy centres under development. This study expresses the views of Proton Therapy experts from 12 US cities based in 9 states with respect to the role of proton therapy in cancer treatment. An E-survey was conducted to assess clinical, technical, educational, and organizational resources and strategies in US -based Proton Beam Therapy facilities and to recognize patters of practice. The E-survey attempted to identify tumours which are more likely to benefit from Proton beam Therapy compared to Photon based Therapy. The role of Proton Beam Therapy in Breast, Brain and Lung cancers was also studied. The study also intended to find what improvements are needed to ensure efficient treatment planning, delivery and dosimetry. This is the first study of its kind in USA.

References

Taqaddas A. Unlocking the Secrets of Proton Beam Therapy. Gamma Gazette. Autumn edition: 2020; 30-33. [online] Available at: https://issuu.com/anzsnm/docs/anzsnm_ gamma_gazette_2020_autumn_edition_final [Accessed 27/11/2021].

Paganetti H. Proton beam therapy. Bristol (GB): IOP Publishing; 2017 [online] Available at: https://iopscience.iop.org/chapter/978-0-7503-1370-4/bk978-0-7503-1370-4ch1.pdf [Accessed 10/12/2021].

Chang A, Yock T, Mahajan A, Hill-Kaiser C, Keole S, Loredo L, Cahlon O, McMullen K, Hartsell W, Indelicato D. Pediatric proton therapy: patterns of care across the United States. International Journal of Particle Therapy 2014; 1(2): 357-67. https://doi.org/10.14338/IJPT.13.00009.1

Stefanowicz S, Stützer K, Zschaeck S, Jakobi A, Troost EG. Comparison of different treatment planning approaches for intensity-modulated proton therapy with simultaneous integrated boost for pancreatic cancer. Radiation Oncology 2018; 13(1): 1-1. https://doi.org/10.1186/s13014-018-1165-0

Florijn M, Sharfo A, Wiggenraad R, van Santvoort J, Petoukhova A, Hoogeman M, Mast M, Dirkx M. Lower doses to hippocampi and other brain structures for skull-base meningiomas with intensity modulated proton therapy compared to photon therapy. Radiotherapy and Oncology 2020; 142: 147-53. https://doi.org/10.1016/j.radonc.2019.08.019

Adeberg S, Harrabi S, Bougatf N, Verma V, Windisch P, Bernhardt D, Combs S, Herfarth K, Debus J, Rieken S. Dosimetric comparison of proton radiation therapy, volumetric modulated arc therapy, and three-dimensional conformal radiotherapy based on intracranial tumor location. Cancers 2018; 10(11): 401. https://doi.org/10.3390/cancers10110401

Dagan R, Bryant C, Bradley J, Indelicato D, Rutenberg M, Rotondo R, Morris C, Mendenhall W. A prospective evaluation of acute toxicity from proton therapy for targets of the parotid region. International Journal of Particle Therapy 2016; 3(2): 285-90. https://doi.org/10.14338/IJPT-16-00010.2

Holliday E, Garden A, Rosenthal D, Fuller C, Morrison W, Gunn G, Phan J, Beadle B, Zhu X, Zhang X, Hanna E. Proton therapy reduces treatment-related toxicities for patients with nasopharyngeal cancer: a case-match control study of intensity-modulated proton therapy and intensity-modulated photon therapy. International Journal of Particle Therapy 2015; 2(1): 19-28. https://doi.org/10.14338/IJPT-15-00011.1

Musielak M, Suchorska WM, Fundowicz M, Milecki P, Malicki J. Future Perspectives of Proton Therapy in Minimizing the Toxicity of Breast Cancer Radiotherapy. Journal of Personalized Medicine 2021; 11(5): 410. https://doi.org/10.3390/jpm11050410

Mast M, Vredeveld E, Credoe H, van Egmond J, Heijenbrok M, Hug E, Kalk P, van Kempen-Harteveld L, Korevaar E, van der Laan H, Langendijk J. Whole breast proton irradiation for maximal reduction of heart dose in breast cancer patients. Breast Cancer Research and Treatment 2014; 148(1): 33-9. https://doi.org/10.1007/s10549-014-3149-6

Ares C, Khan S, MacArtain A, Heuberger J, Goitein G, Gruber G, Lutters G, Hug E, Bodis S, Lomax A. Postoperative proton radiotherapy for localized and locoregional breast cancer: potential for clinically relevant improvements? International Journal of Radiation Oncology Biology Physics 2010; 76(3): 685-97. https://doi.org/10.1016/j.ijrobp.2009.02.062

Han Y. Current status of proton therapy techniques for lung cancer. Radiation Oncology Journal 2019; 37(4): 232. https://doi.org/10.3857/roj.2019.00633

RaySearch Laboratories. RayStation Comprehensive Cancer Treatment Planning [online]. 2021. Available at: https://www.raysearchlabs.com/raystation/ [Accessed 10/12/2021]

Hrbacek J, Mishra K, Kacperek A, Dendale R, Nauraye C, Auger M, Herault J, Daftari IK, Trofimov A, Shih H, Chen Y. Practice patterns analysis of ocular proton therapy centers: the international OPTIC survey. International Journal of Radiation Oncology Biology Physics 2016; 95(1): 336-43. https://doi.org/10.1016/j.ijrobp.2016.01.040

Schulte R. Strategies for image-guided proton therapy of cancer. US Oncological Disease 2007; 1(1): 75-7. https://doi.org/10.17925/OHR.2007.00.01.75

Brousmiche S, Seabra J, Labarbe R, Vila Oliva M, Rit S, et al. Design of cone-beam CT for proton therapy gantry. ESTRO 33, 2014, Vienne, Austria. pp. PO-0783. https://doi.org/10.1016/S0167-8140(15)30901-4

Zhang M, Zou W, Teo B. Image guidance in proton therapy for lung cancer. Translational Lung Cancer Research 2018; 7(2): 160. https://doi.org/10.21037/tlcr.2018.03.26

Ding X, Zheng Y, Zeidan O, Mascia A, Hsi W, Kang Y, Ramirez E, Schreuder N, Harris B. A novel daily QA system for proton therapy. Journal of Applied Clinical Medical Physics 2013; 14(2): 115-26. https://doi.org/10.1120/jacmp.v14i2.4058

Actis O, Meer D, König S, Weber D, Mayor A. A comprehensive and efficient daily quality assurance for PBS proton therapy. Physics in Medicine & Biology 2017; 62(5): 1661. https://doi.org/10.1088/1361-6560/aa5131

Arjomandy B, Taylor P, Ainsley C, Safai S, Sahoo N, Pankuch M, Farr J, Yong Park S, Klein E, Flanz J, Yorke E. AAPM task group 224: Comprehensive proton therapy machine quality assurance. Medical Physics 2019; 46(8): e678-705. https://doi.org/10.1002/mp.13622

The National association for Proton Therapy. Proton therapy centers in U.S. 2021 [online] Available at: https://www.proton-therapy.org/map/ [Accessed 27/12/2021].

Joint Technical Committee OB/7. AS NZS 4360: 1999 Risk Management. Strathfield NSW. Standards Association of Australia; 1999 [online] Available at: http://www.epsonet.eu/ mediapool/72/723588/data/2017/AS_NZS_4360-1999_Risk_management.pdf [Accessed 10/12/2021].

Risk Management Plan for Research on the Alfred Campus. Australia. Alfred Campus; 2004. [online] Available at: https://www.alfredhealth.org.au/images/resources/research/Risk-management-plan.pdf [Accessed 10/12/2021]

A guide to the Project Management Body of Knowledge (PMBOK Guide®). 2000 ed. Pennsylvania (USA): Project Management Institute, Inc; 2000. Chapter 11, Project Risk Management; p.127-146.

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Published

2021-12-07

Issue

Vol. 10 (2021)

Section

Articles

How to Cite

E-Survey: Current Status of Proton Beam Therapy in USA. (2021). Journal of Analytical Oncology, 10, 32-60. https://doi.org/10.30683/1927-7229.2021.10.05

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