Solitary Extramedullary Plasmocytoma of the Thyroid Gland: A Case Report
- Authors
-
-
Martin Balog
Klinik für Allgemein-und Viszeralchirurgie, Thoraxchirurgie und Proktologie des Klinikums Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany -
Ulrich Lang
Institut für Pathologie, Klinikum Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany -
Günther Winde
Klinik für Allgemein-und Viszeralchirurgie, Thoraxchirurgie und Proktologie des Klinikums Herford, Schwarzenmoorstrasse 70, 32049 Herford, Germany
-
- Keywords:
- Solitary, plasmocytoma, extramedullary, thyroid, multiple myeloma.
- Abstract
-
Solitary extramedullary plasmocytoma (SEP) of the thyroid gland is a very rare disease. The diagnosis of SEP can be made after ruling out multiple myeloma. Histological examinations, immunohistochemical analysis with an overexpression of CD 138, CD 38 and kappa light chain reaction confirmed this uncommon condition in our case. Medullary carcinoma, MALT-Lymphoma and Non-Hodgkin Lymphoma of the thyroid should be excluded in the diagnosis.
Surgical resection and radiotherapy, or a combination of both, are standard treatment methods. However, because of rareness of this disease, no general therapy can be recommended.
We report about a 75 year old male patient and its involvement of the right remainder thyroid lobe by SEP five years post a Dunhill-Procedure due to multinodular goiter.
- References
-
Voegt H. Extramedullare plasmacytome.Virch Arch Pathol Anat 1938; 302: 497-508. http://dx.doi.org/10.1007/BF02595118
Kovacs CS, Mant MJ, Nguyen GK, et al. Plasma cell lesions of the thyroid: report of a case of solitary plasmocytoma and review of the literature. Thyroid 1994; 4: 65-71. http://dx.doi.org/10.1089/thy.1994.4.65
Beguin Y, Boniver J, Bury J, et al. Plasmocytoma of the thyroid: a case report, a study with use of ummunoperoxidase technique, and a review of the literature. Surgery 1987; 101(4): 496-500.
Mekkavy AA. Plasmocytoma of the thyroid gland: case report and review of the literature, JKAU Medical Science 2010; 17(2):83-92.
Kuo SF, Chang HY, Hsueh C, et al. Extramedullary plasmocytoma of the thyroid. NZ Med J 2006; 119(1235): U2005.
Kapadia SB, Desai U, Cheng VS. Extramedullary plasmocytoma of the head and neck. A clinicopathologic study of 20 cases. Medicine 1982; 61: 317-329. http://dx.doi.org/10.1097/00005792-198209000-00004
Wax MK, Yun KJ, Omar RA. Extramedullary plasmocytomas of the head and neck. Otolaryngology 1993; 109(5): 877-885.
Galieni P, Cavo M, Pulsoni A, et al. Clinical outcome of extramedullary plasmocytoma. Haematologica 2000; 85(1): 47-51.
Alexiou C, Kau RJ, Dietzfelbinger H, et al. Extramedullary plasmocytoma, tumor occurrence and therapeutic concepts. Cancer 1999; 85(11): 2305-2314. http://dx.doi.org/10.1002/(SICI)1097-0142(19990601)85:11<2305::AID-CNCR2>3.0.CO;2-3
Soutar R, Lucraft H, Jacson G, et al. Guidelines on the diagnosis and management of solitary plasmocytoma of bone and solitary extramedullary plasmocytoma. Clinical Oncology 2004; 16(6): 405-413. http://dx.doi.org/10.1016/j.clon.2004.02.007
Bhat V, Shariff S, Reddy RA. Extramedullary plasmocytoma of thyroid-a mimicker od medellary carcinoma at fine needle aspiration cytology: A case report. J Cytol 2014; 31(1): 53-6. http://dx.doi.org/10.4103/0970-9371.130710
- Downloads
- Published
- 2015-01-09
- Issue
- Vol. 4 No. 1 (2015)
- Section
- Articles
How to Cite
Similar Articles
- Hassan Akbari, Farzad Taghizadeh Hesary, Laya Rahnar Nikoukar, Distribution of Breast Cancer Biomarkers by Age in Iran , Journal of Analytical Oncology: Vol. 6 No. 1 (2017)
- Kenji Ina, Ryuichi Furuta, Takae Kataoka, Sayaka Sugiura, Satoshi Kayukawa, Takayuki Kanamori, Takaki Kikuchi, Megumi Kabeya, Satoshi Hibi , Shu Yuasa , Adverse Effects of Bevacizumab During Treatment for Metastatic Colorectal Cancer , Journal of Analytical Oncology: Vol. 4 No. 1 (2015)
- Rahul G. Dholariya, Ankur Tripathi, Amritha Prabha Shankar, M.S. Ganesh, Ravoori Harish Babu, Prevalence and Type Distribution of Human Papilloma Virus (HPV) in Oral, Oropharyngeal, Cervical, and Vulvovaginal Cancers , Journal of Analytical Oncology: Vol. 14 (2025)
- Bernardo Garicochea, Alessandro Igor Cavalcanti Leal, Fernando Sérgio Blumm Ferreira, Volney Assis Lara Vilela, Alesso Cervantes Sartorelli, Yana Novis, Paulo Marcelo Gehm Hoff , Angioimmunoblastic T-Cell Lymphoma: Clinical Aspects and Recent Advances in Biology and Therapy , Journal of Analytical Oncology: Vol. 3 No. 4 (2014)
- Krishnendu Ghosh, Jayanta Kumar Chandra, Anirban Ghosh, Brain Tumour Classification by Machine Learning Applications with Selected Biological Features: Towards A Newer Diagnostic Regime , Journal of Analytical Oncology: Vol. 9 (2020)
- Shu Yuasa, Megumi Kabeya, Ryuichi Furuta, Satoshi Hib, Chiaki Koga, Seiji Nagao, and Kenji Ina, A Case of Sigmoid Colon Cancer in which Somatic Pain was Rapidly Alleviated after Panitumumab Administration Despite Tumor Progression , Journal of Analytical Oncology: Vol. 5 No. 1 (2016)
- Robert Skopec, Mutagenesis Associated with DNA-Damage-Stress Response , Journal of Analytical Oncology: Vol. 5 No. 1 (2016)
- Mathilde E. Boon, Joke A.M. Dols, Nicodemus Butamanya, Gregor Reid, The Cellient System for Cytohistology to Analyze p16 Positive Dyskeratocytes in Paraffin Sections of HPV-Positive Cervical Scrapes , Journal of Analytical Oncology: Vol. 1 No. 1 (2012)
- Ahmed Abdullah Alhumaidi, Elastic Tissue in Nevus Lipomatosus Cutaneous Superficialis , Journal of Analytical Oncology: Vol. 2 No. 2 (2013)
- Michael T. Halpern, Susan G. Haber, Florence K. Tangka, Susan A. Sabatino, David H. Howard, Sujha Subramanian, Cancer Screening Among U.S. Medicaid Enrollees with Chronic Comorbidities or Residing in Long-Term Care Facilities , Journal of Analytical Oncology: Vol. 2 No. 2 (2013)
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Martin Balog, Ulrich Lang , Günther Winde , Buschke Löwenstein Tumor of the Right Lower Abdominal Wall: Case Report and Review of the Literature , Journal of Analytical Oncology: Vol. 4 No. 1 (2015)