Cancer: Evidence Consistent with Epigenetic Carcinogenesis




Malignant phenotype, abnormal transmigration, gene silencing, DNA methylation, defective epigenetic copying, initiation, promotion


This brief review outlines the accumulated evidence which favours a mechanism of cancer generation that is dependent on defective vertical transmission of the pattern of epigenetic control of genetic expression. This model is based on the initiating lesion involving the process that copies the epigenetic features when stem cells undergo mitosis.


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How to Cite

Riley, P. A. (2022). Cancer: Evidence Consistent with Epigenetic Carcinogenesis. Journal of Cancer Research Updates, 11, 39–42.