Short-Time Outcome of Intraoperative Radiotherapy (IORT): A Study on Side-Effects and Quality of Life in the Treatment of Early Breast Cancer


  • Caroline Page Lausanne University, Lausanne, Switzerland
  • Pierre-Alain Brioschi Department of Gynecology, Clinique de Genolier, Genolier, Switzerland
  • Jacques Bernier Department of Radiation Oncology, Clinique de Genolier, Genolier, Switzerland



Breast Cancer, Intraoperative radiation therapy, Radiation therapy, Side-effect, Cosmetics.


 Early prospective studies recently demonstrated the non-inferiority of intraoperative radiotherapy compared to protracted external radiotherapy in selected patients. The present study aims at analyzing, in a cohort of 80 women,the distribution and incidence of short-time side-effects induced by intraoperative radiotherapy as well as its impact on patient's quality of life in the months following the treatment. No side-effect was found in the majority of patients (n: 46; 58%). Out of those 32 patients experiencing side-effects after IORT, 26 cases (81%) were found to develop only mild effects. More than 94% of the patients declared to consider IORT as a clear advantage over external radiotherapy in the armamentarium of breast cancer treatment.


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How to Cite

Caroline Page, Pierre-Alain Brioschi, & Jacques Bernier. (2013). Short-Time Outcome of Intraoperative Radiotherapy (IORT): A Study on Side-Effects and Quality of Life in the Treatment of Early Breast Cancer. Journal of Cancer Research Updates, 2(4),  237–245.