Second Look Proactive Surgery for Colon Cancer with Peritoneal Carcinomatosis

Halkia Evgenia; Spiliotis John; Sugarbaker Paul

doi:10.6000/1929-2279.2012.01.02.9

Authors

Halkia Evgenia Washington Cancer Institute, USA
Spiliotis John Metaxa Cancer Memorial Hospital, Greece
Sugarbaker Paul Washington Cancer Institute, USA

DOI:

https://doi.org/10.6000/1929-2279.2012.01.02.9

Keywords:

Peritoneal carcinomatosis colorectal cancer HIPEC.

Abstract

Second look surgery in patients with colorectal cancer has always been, a controversial subject. The surgical literature suggests benefit in a re operation, where a limited extent of cancer is discovered and then resected with negative surgical margins. This paper seeks to identify the clinical factors that predispose to the recurrence of a primary colorectal cancer and the benefit of a second look surgery. It represents the attitude of a new treatment strategy in cases that the patient develops peritoneal metastasis at the initial operation and after an adjuvant treatment with systemic chemotherapy. We also discuss the intra-operative criteria, especially after the initial operation, in order to propose a therapeutic algorithm in the management of advanced colorectal disease.

References

Sugarbaker PH, Second-Look Surgery for Colorectal Cancer: Revised Selection Factors and New Treatment Options for Greater Success. Int J Surg Oncol 2011; 8. http://dx.doi.org/10.1155/2011/915078

Ostan RT, Guyton S, Steele G Jr, Wilson RE. Malignant intestinal obstruction. Surgery 1980; 87(6): 611-15.

Jacquet P, Sugarbaker PH. Clinical research methodologies in dignosis nd stging o ptient with peritoneal carcinomatosis. In Peritoneal carcinomatosis principles of management edited by Sugarbaker PH Boston Klwwer Academic publishers 996; 359-374.

Butler JA, Cameron BL, Morrow M, Khang K, Torn J. Small bowel obstruction in patients with a prior history of cancer. Am J Surg 1991; 162(6): 624-28. http://dx.doi.org/10.1016/0002-9610(91)90123-U

Walsh HPJ, Schofield PF. Is laparotomy for small bowel obstruction justified in patients with previously treated malignancy? Br J Surg 1984; 71(12): 933-35. http://dx.doi.org/10.1002/bjs.1800711206

Spears H, Petrelli MJ, Herrera L, Mittelman A. Treatment of bowel obstruction after operation for colorectal carcinoma. Am J Surg 1988; 155(3): 383-86. http://dx.doi.org/10.1016/S0002-9610(88)80095-3

Minton JP, Hoehn JL, Gerber DM. Results of a 400-patient carcinoembryonic antigen second-look colorectal study. Cancer 1985; 55(6): 1284-90. http://dx.doi.org/10.1002/1097-0142(19850315)55:6<1284::AID-CNCR2820550622>3.0.CO;2-B

Sugarbaker PH, Zamcheck N, Moore FD. Assessment of serial carcinoembryonic antigen (CEA) assays in post-operative detection of recurrent colorectal cancer. Cancer 1976; 38(6): 2310-15. http://dx.doi.org/10.1002/1097-0142(197612)38:6<2310::AID-CNCR2820380618>3.0.CO;2-L

Yan TD, Black D, Savady R, Sugarbaker PH. Systematic review on efficacy of cytoreductive surgery combined with perioperative intra-peritoneal chemotherapy for peritoneal carcinomatosis from colorectal carcinoma. J Clin Oncol 2006; 24(24): 4011-14. http://dx.doi.org/10.1200/JCO.2006.07.1142

Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3/U0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003; 10(1): 65-71. http://dx.doi.org/10.1245/ASO.2003.03.058

Rich T, Gunderson LL, Galdabini J, et al. Clinical and pathologic factors influencing local failure after curative resection of carcinoma of the rectum and rectosigmoid. Cancer 1983; 52: 317-27. http://dx.doi.org/10.1002/1097-0142(19831001)52:7<1317::AID-CNCR2820520731>3.0.CO;2-6

Sugarbaker PH. Successful management of microscopic residual disease in large bowel cancer. Cancer Chemother Pharmacol 1999; 43(Suppl): 515-25. http://dx.doi.org/10.1007/s002800051093

Sugarbaker PH, Gunderson LL, Wittes RE. Colorectal cancer. in Cancer: Principles and Practice of Oncology, V.T. De Vita Jr., S. Hellman, and S.A. Rosenberg, Eds., J.B. Lippincott, Philadelphia, Penn, USA 1985; vol. 1: pp. 795-866.

Sugarbaker PH, Jablonski KA. Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intra-peritoneal chemotherapy. Ann Surg 1995; 221: 124-32. http://dx.doi.org/10.1097/00000658-199502000-00002

Elias D, Goéré D, Di Pietrantonio D, et al. Results of systematic second-look surgery in patients at high risk of developing colorectal peritoneal carcinomatosis. Ann Surg 2008; 247(3):, 445-50. http://dx.doi.org/10.1097/SLA.0b013e31815f0113

Sugarbaker PH. Monitoring after resection of upper and lower gastrointestinal cancer in Surgery for Gastrointestinal Cancer: A Multidisciplinary approach, Wanebo HJ, Ed. Lippincott – Raven Publishers, Philadelphia, Penn, U.S.A., 1997; pp. 87-95.

Sugarbaker PH. Peritonectomy procedures. Surg Oncol Clin N Am 2003; 12(3): 703-27. http://dx.doi.org/10.1016/S1055-3207(03)00048-6

Van Der Speeten K, Stuart OA, Sugarbaker PH. Pharmacokinetics and pharmacodynamics of peri-operative cancer chemotherapy in peritoneal surface malignancy. Cancer J 2009; 15(3): 216-24. http://dx.doi.org/10.1097/PPO.0b013e3181a58d95

Spiliotis J. Peritoneal carcinmatosis cytoreductive surgery and HIPEC: A ray of hope for cure. Hepato-Gastroenterology 2010; 57: 1173-77.