Concurrent Plasma Cell Mastitis and Metastatic Breast Cancer a Rare Presentation of a Bilateral Disease: Case Report and Literature Review

Concurrent Plasma Cell Mastitis and Metastatic Breast Cancer a Rare Presentation of a Bilateral Disease: Case Report and Literature Review

Authors

  • Joseph E. Udosen Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria
  • John A. Ashindoitiang Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria https://orcid.org/0000-0003-0763-9707
  • Victor I.C. Nwagbara Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria
  • Theophilus I. Ugbem Department of Pathology, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria
  • Joseph S. Ukam Department of Surgery, University of Calabar Teaching Hospital, Calabar, Nigeria
  • Maurice E. Asuquo Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria

DOI:

https://doi.org/10.30683/1927-7229.2024.13.05

Keywords:

Plasma cell mastitis, Benign disease, Breast cancer, Metastatic, Concurrent, Bilateral

Abstract

The concurrent occurrence of plasma cell mastitis(PCM) and breast cancer is rare. Plasma cell mastitis(PCM) is a chronic inflammatory breast disease. Metastatic breast cancer(MBC) is breast cancer that has spread to another part of the body commonly the bones, lungs, liver or brain. Presented is a 28 year old woman who was seen at the emergency department with difficulty in breathing and abdominal swelling of one month and two weeks duration respectively. In the previous year, she was diagnosed with bilateral PCM but declined therapy. Clinical, imaging and laboratory evaluation revealed a definitive diagnosis of metastatic bilateral breast cancer. Reported is a bilateral PCM and a metastatic bilateral invasive ductal carcinoma(IDC). PCM should be regarded as a key alert for a persistent check for cancer. Timely diagnosis and prompt surgical removal is recommended for the best possible outcomes.

References

Salih AM, Pshtiwan LR, Abdullah AM, Dhahir HM, Ali HO, Muhiaiden AS, Hussein BO, Hassan SH, Kakamab FH. Granulomatous mastitis masking ductal carcinoma in situ: A case report with literature review. Biomedical Reports 2024; 20: 17. https://doi.org/10.3892/br.2023.1705 DOI: https://doi.org/10.3892/br.2023.1705

Ashindoitiang J, Nwagbara V, Ugbem T, Ukam J, Asuquo M. Bilateral plasma cell mastitis simulating breast cancer: a case report and literature review. Journal of International Medical Research 2024; 52(3): 1-6. https://doi.org/10.1177/03000605241233167 DOI: https://doi.org/10.1177/03000605241233167

Adisa AO, Arowolo OA, Akinkuolie AA, Titiloye NA, Alatise OI, Lawal OO, Adesillonwo ARK. Metastatic breast cancer in a Nigerian tertiary hospital. African Health Science 2011; 11(2): 279-284.

Tavacol M, Alvand S, Azmoadeh AF, Ardalan A, Assavian A. Idiopathic granulomatous mastitis with incidental lobular carcinoma in situ: A case report. Arch Breast 2022; 9: 315-319. https://doi.org/10.32768/abc.202293SI315-319 DOI: https://doi.org/10.32768/abc.202293SI315-319

Handley WS. Chronic mastitis and breast cancer. Br Med J 1938; 2: 113-138. https://doi.org/10.1136/bmj.2.4045.113 DOI: https://doi.org/10.1136/bmj.2.4045.113

Salih AM, Pshtiwan LR, Abdullah AM, Qaradakhy AJ, Kadamad FH, Ali HO, Salih KM, Rahim HM, Abdalla BA, Hassan MN, Mohammed SH. Carcinoma arising from fibroadenoma: presentation and management: a case series. Barw Med J 2023; 1: 1-28.

Evans J, Sisk L, Chi K, Brown S, To H. Concurrent granulomatous mastitis and invasive ductal cancer in contralateral breasts- a case report and review. J Surg Case Reps 2021; 11: 1-3. https://doi.org/10.1093/jscr/rjab519 DOI: https://doi.org/10.1093/jscr/rjab519

Yoshida N, Nakatsubo M, Yoshino R, Ho A, Ujiie N, Yazawa S, Kitoda M. Concurrent granulomatous mastitis and ductal carcinoma in situ. Cureus 2023; 15(5): e38377. https://doi.org/10.7759/cureus.38377 DOI: https://doi.org/10.7759/cureus.38377

Bacon DR, Ngeve SM, Jordan SG. Granulomatous mastitis. An undiagnosed inflammatory disease afflicting minority of women. Radiol Care Rep 2021; 16: 3990-3994. https://doi.org/10.1016/j.radcr.2021.09.044 DOI: https://doi.org/10.1016/j.radcr.2021.09.044

Cahs H, Kihtei A. Granulomatous mastitis concurrence with breast cancer. Eur J Breast Health 2018; 14: 58-60. https://doi.org/10.5152/ejbh.2017.3804 DOI: https://doi.org/10.5152/ejbh.2017.3804

Oddo D, Dominguez F, Gomez N, Mendez GP, Navarro ME. Granulomatous lobular mastitis associated with ductal carcinoma in situ of the breast. SAGE Open Med Case Rep 2019; 7: 2050313x19836583. https://doi.org/10.1177/2050313X19836583 DOI: https://doi.org/10.1177/2050313X19836583

Chen Y, Chan C, Lim Y, Yang S, Yeh L, Wang Y, Chou M, Yeh C. Risk of breast cancer in women with mastitis: A retrospective population based cohort study. Medicina 2020; 56: 372. https://doi.org/10.3390/medicina56080372 DOI: https://doi.org/10.3390/medicina56080372

Yin Y, Liu X, Mang G, Han X, Zhang H, Lv Y. Idiopathic granulomatous mastitis: etiology, clinical manifestations, diagnosis and treatment. J Invest Surg 2022; 35(3): 709-720. https://doi.org/10.1080/08941939.2021.1894516 DOI: https://doi.org/10.1080/08941939.2021.1894516

Kessler E, Welloch Y, Granulomatous mastitis: A lesion clinically simulating cancer. Am J Clin Pathol 1972: 58: 642-646. https://doi.org/10.1093/ajcp/58.6.642 DOI: https://doi.org/10.1093/ajcp/58.6.642

Waraya M, Inukai M. A case report of triple negative breast cancer diagnosed as GM. J Cancer Chemother 2020; 47: 1854-1856.

Zhu Q, Wang L, Wang P. The identification of gene expression profiles associated with granulomatous mastitis. Breast Care 2021; 16: 319-326. https://doi.org/10.1159/000507474 DOI: https://doi.org/10.1159/000507474

Aksan H, Kundaktepe BP, Sayili U, Validedeoglu M, Simell G, Koksal S et al. Circulating miR-155, let-7c, miR-21 and PTEN levels in differential diagnosis and prognosis of idiopathic granulomatous mastitis and breast cancer. Biofactors 2020; 46: 955-962. https://doi.org/10.1002/biof.1676 DOI: https://doi.org/10.1002/biof.1676

Chen R, Hu B, Zhang Y, Liu C, Zhao L, Jiang Y, Xu Y. Differential diagnosis of plasma cell mastitis and invasive ductal carcinoma using multiparametric MRI. Gland Surg 2020; 9(2): 278-290. https://doi.org/10.21037/gs.2020.03.30 DOI: https://doi.org/10.21037/gs.2020.03.30

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Published

2024-12-02

How to Cite

Udosen, J. E. ., Ashindoitiang, J. A. ., Nwagbara, V. I. ., Ugbem, T. I. ., Ukam, J. S. ., & Asuquo, M. E. . (2024). Concurrent Plasma Cell Mastitis and Metastatic Breast Cancer a Rare Presentation of a Bilateral Disease: Case Report and Literature Review. Journal of Analytical Oncology, 13, 29–35. https://doi.org/10.30683/1927-7229.2024.13.05

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