Elastic Tissue in Nevus Lipomatosus Cutaneous Superficialis
DOI:
https://doi.org/10.6000/1927-7229.2013.02.02.8Keywords:
Nevus lipomatosus superficialis, elastic fibers.Abstract
Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign hamartomatous condition characterized by the presence of mature ectopic adipocytes in the dermis. We studied twelve cases of solitary type of NLCS to demonstrate the status of elastic fibers. All were stained with elastic-van Gieson stain for elastic tissue. Most of the cases showed moderate to marked reduction and thinning of elastic fibers (EF) as compared to adjacent normal dermis. We conclude that thinned and decreased elastic tissue is the cause of NLCS.
References
Hoffmann E, Zurhelle E. Über einen naevus lipomatodes cutaneus superficialis der linken glutaalgegend. Arch Dermatol Syphilol 1921; 130: 327-33.
Metin A, Calka O, Akpolat N. Nevus lipomatosus cutaneous superficialis (Hoffmann-Zurhelle). Eastern J Med 2001; 6: 26-8.
Dhar S, Kumar B, Kaur I. Naevus lipomatosus superficialis of Hoffmann and Zurhelle. Indian J Dermatol Venereol Leprol 1994; 60: 39-40.
Lever's histopathology of the skin. 10th ed. New Delhi: Wolters Kluwer- Lippincott Williams and Wilkins; 2009; pp. 1057-106.
Thappa DM, Sharma RC, Lal S, Logani KB. Naevus lipomatosus cutaneous superficialis: Report of 2 cases. Indian J Dermatol Venereol Leprol 1992; 58: 27-9.
Cay M. Kielty, Michael J. Sherratt, C. Adrian Shuttleworth, elastic fibers. J Cell Sci 2002; 115: 2817-28.
