A Study to Investigate the Role of Noncoding RNA miR146 Alpha as a Potential Biomarker in Prostate Cancer

Authors

  • Myla Worthington Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Chelsey Aurelus Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Narendra Banerjee Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Christopher Krauss Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • William Kahan Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Satyendra Banerjee Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Sherita Gavin Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Victoria Bartlett Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Gloria Payne Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Jeffrey Rousch Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA
  • Mukesh Verma Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Suite 4E102, 9609 Medical Center Drive, Bethesda, USA
  • Fazlul Sarkar Department of Pathology, Wayne State University and Barbara Karmanos Cancer Center, Detroit, USA
  • Hirendra Nath Banerjee Department of Natural Sciences, Elizabeth City State University, University of North Carolina, NC 27909, USA

DOI:

https://doi.org/10.30683/1927-7229.2022.11.03

Keywords:

Prostate Cancer, Non Coding RNA, miR146 alpha, Biomarker

Abstract

There is a need for additional biomarkers for the diagnosis and prognosis of prostate cancer. MicroRNAs are a class of non-protein coding RNA molecules that are frequently dysregulated in different cancers including prostate cancer and show promise as diagnostic biomarkers and targets for therapy. Here we describe the role of micro RNA 146 a (miR-146a) which may serve as a diagnostic marker for prostate cancer, as indicated from the data presented in this report. Also, a pilot study indicated differential expression of miR-146a in prostate cancer cell lines and tissues from different racial groups. This report provides a novel insight into understanding the prostate carcinogenesis.

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Published

2022-07-22

How to Cite

Worthington, M., Aurelus, C., Banerjee, N., Krauss, C., Kahan, W., Banerjee, S., Gavin, S., Bartlett, V., Payne, G., Rousch, J., Verma, M., Sarkar, F., & Banerjee, H. N. (2022). A Study to Investigate the Role of Noncoding RNA miR146 Alpha as a Potential Biomarker in Prostate Cancer. Journal of Analytical Oncology, 11, 21–23. https://doi.org/10.30683/1927-7229.2022.11.03

Issue

Vol. 11 (2022)

Section

Articles

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