Effective and Rapid Osteoclast Inhibition by Denosumab, is Reflected in Serum C Telopeptide (CTX), Across Different Tumor Types

Authors

  • S. Tuyls Depts. of Medical Oncology, Regional Hospital Sint Maria, Ziekenhuislaan 100, 1500 Halle, Belgium
  • F. Geurs Depts. of Medical Oncology, Regional Hospital Sint Maria, Ziekenhuislaan 100, 1500 Halle, Belgium
  • Y. Deprest Laboratory, Regional Hospital Sint Maria, Ziekenhuislaan 100, 1500 Halle, Belgium

DOI:

https://doi.org/10.6000/1927-7229.2013.02.02.1

Keywords:

Bone metastases, denosumab, serum c telopeptide.

Abstract

Denosumab, a monoclonal antibody against RANKL has superior efficacy against bone metastases. Its in vivo activity can be measured recently by dosing of serum C telopeptide, produced by collagen destruction by the osteoclast. We report the first patient series, across several tumor types of the efficacy of denosumab in normalising serum CTX.

References

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Published

2013-04-03

How to Cite

S. Tuyls, F. Geurs, & Y. Deprest. (2013). Effective and Rapid Osteoclast Inhibition by Denosumab, is Reflected in Serum C Telopeptide (CTX), Across Different Tumor Types. Journal of Analytical Oncology, 2(2),  58–61. https://doi.org/10.6000/1927-7229.2013.02.02.1

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Articles