The Predictors of Multicentricity in Well-Differentiated Thyroid Cancer
Keywords:Multifocality, papillary, thyroid nodule, hemithyroidectomy, total thyroidectomy.
Introduction: The detection of the multicentericity of thyroid cancer is essential to provide the appropriate surgical decision for the patients aiming to decrease the rate of redo surgery and recurrence
Methods: A cohort study was conducted at the surgical unit of the oncology center, Mansoura university on fifty patients with well-differentiated thyroid cancer, all of them underwent total thyroidectomy then entire gland dissection technique for histopathological examination.
Results: Preoperative radiology revealed unicentric suspicious nodules in 40 cases (80%) and no suspicious nodules in 10 cases (20%). Among the ten patients those showed no suspicious nodules radiologically, multicentricity was confirmed in 5 patients (50%) pathologically, and unicentric tumors was seen in 5 patients (50%). FNAC was done in the 40 mentioned cases and was diagnostic for them as papillary thyroid carcinoma. Among many variants of prediction during searching for the true incidence of multicentricity, only isthmic invasion and, the extra thyroid extension were the significant variants.
Conclusion: Among many variants of prediction during searching for the true incidence of multicentricity, only isthmic invasion and, the extra thyroid extension were the significant variants.
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