Strength Training as an Adjunct to the Maintenance of Muscle Mass in Patients with Head and Neck Cancer
DOI:
https://doi.org/10.6000/1927-7229.2018.07.02.1Keywords:
Cancer, exercise, strength training, health.Abstract
Head and neck cancer (HNC) is one of the most common types of the disease, particularly among men, and is characterized by a high incidence of death. Among the non-pharmacological factors that help in survival and improving quality of life is physical exercise, especially strength training. The purpose of this short communication was to briefly review the literature and present a training proposal for oncology patients with HNC. Evidence is provided that physical exercise, mainly short-term strength (HIIT [High-Intensity Interval Training]) and aerobic training, contributes to increased expectation and quality of life in cancer survivors. After reviewing the current state of literature, we conclude that strength training, by providing maintenance of muscle mass, improves the autonomy and quality of life of oncology patients with HNC.
References
Gupta B, Johnson NW, Kumar N. Global Epidemiology of Head and Neck Cancers: A Continuing Challenge. Oncology 2016; 91(1): 13-23. https://doi:10.1159/000446117
Lonkvist CK, Lønbro S, Vinther A, Zerahn B, Rosenbom E, Primdahl H, et al. Progressive resistance training in head and neck cancer patients during concomitant chemoradiotherapy -- design of the DAHANCA 31 randomized trial. BMC Cancer 2017; 3; 17(1): 400. https://doi:10.1186/s12885-017-3388-0
Thorsen L, Nilsen TS, Raastad T, Courneya KS, Skovlund E, Fossa SD. A randomized controlled trial on the effectiveness of strength training on clinical and muscle cellular outcomes in patients with prostate cancer during androgen deprivation therapy: rationale and design. BMC Cancer 2012; 12: 123. https://doi:10.1186/1471-2407-12-123
Nilsen TS, Raastad T, Skovlund E, Courneya KS, Langberg CW, Lilleby W, et al. Effects of strength training on body composition, physical functioning, and quality of life in prostate cancer patients during androgen deprivation therapy. Acta Oncol 2015; 54(10): 1805-13. https://doi:10.3109/0284186X.2015.1037008
Lonkvist CK, Vinther A, Zerahn B, Rosenbom E, Deshmukh AS, Hojman P, et al. Progressive resistance training in head and neck cancer patients undergoing concomitant chemoradiotherapy. Laryngoscope Investig Otolaryngol 2017; 2(5): 295–306. https://doi:10.1002/lio2.88
Sandmael JA, Bye A, Solheim TS, Stene GB, Thorsen L, Kaasa S, et al. Feasibility and preliminary effects of resistance training and nutritional supplements during versus after radiotherapy in patients with head and neck cancer: A pilot randomized trial. Cancer 2017; 15; 123(22): 4440-448. https://doi:10.1002/cncr.30901
van Nieuwenhuizen AJ, Buffart LM, van Uden-Kraan CF, van der Velden LA, Lacko M, Brug J, et al. Patient-reported physical activity and the association with health-related quality of life in head and neck cancer survivors. Support Care Cancer 2018; 26(4): 1087-095. https://doi:10.1007/s00520-017-3926-y
Dev R, Del Fabbro E, Bruera E. Outcomes of novel trials for cancer cachexia. Clin Invest 2014; 4(3): 247-57. https://doi:10.4155/CLI.14.9
Solheim TS, Laird BJA, Balstad TR, Bye A, Stene G, Baracos V, et al. Cancer cachexia: rationale for the MENAC (Multimodal-Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial. BMJ Supportive & Palliative Care 2018; 0: 1-8. https://doi:10.1136/bmjspcare-2017-001440
Meriggi F. Cancer Cachexia: One Step Ahead. Rev Recent Clin Trials 2015; 10(3): 246-50. https://doi:10.2174/1574887110666150916141351
Argilés JM, Busquets S, Stemmler B, López-Soriano FJ. Cancer cachexia: understanding the molecular basis. Nat Rev Cancer 2014; 14(11): 754-62. https://doi:10.1038/nrc3829
Grande AJ, Silva V, Riera R, Medeiros A, Vitoriano SGP, Peccin MS, et al. Exercise for cancer cachexia in adults. Cochrane Database Syst Rev 2014; 26(11): CD010804. https://doi:10.1002/14651858.CD010804.pub2
Wilson JM, Marin PJ, Rhea MR, Wilson SMC, Loenneke JP, Anderson JC. Concurrent training: a meta-analysis examining interference of aerobic and resistance exercise. J Strength Cond Res 2012; 26(8): 2293-307. https://doi:10.1519/JSC.0b013e31823a3e2d
Fyfe JJ, Bishop DJ, Stepto NK. Interference between concurrent resistance and endurance exercise: molecular bases and the role of individual training variables. Sports Med 2014; 44(6): 743-62. https://doi:10.1007/s40279-014-0162-1
Spiering BA, Kraemer WJ, Anderson JM, Armstrong LE, Nindl BC, Volek JS, et al. Manipulation of resistance exercise programme variables determines the responses of cellular and molecular signaling pathways. Sports Med 2008; 38(7): 527-540. https://doi:10.2165/00007256-200838070-00001
Gundersen K. Muscle memory and a new cellular model for muscle atrophy and hypertrophy. J Exp Biol 2016; 219(2): 235-42. https://doi:10.1242/jeb.124495
Murach KA, Bagley JR. Skeletal muscle hypertrophy with concurrent exercise training: contrary evidence for an interference effect. Sports Med 2016; 46(8): 1029-39. https://doi:10.1007/s40279-016-0496-y
Toohey K, Pumpa K, McKune A, Cooke J, DuBose KD, Yip D, et al. Does low volume high-intensity interval training elicit superior benefits to continuous low to moderate-intensity training in cancer survivors? World J Clin Oncol 2018; 10; 9(1): 1-12. https://doi:10.5306/wjco.v9.i1.1
Jackson C, Dowd AJ, Capozzi LC, Bridel W, Lau HY, Culos-Reed SN. A turning point: Head and neck cancer patients' exercise preferences and barriers before and after participation in an exercise intervention. Eur J Cancer Care (Engl) 2018; 27(2): e12826. https://doi:10.1111/ecc.12826
Midgley AW, Lowe D, Levy AR, Mepani V, Rogers SN. Exercise program design considerations for head and neck cancer survivors. Eur Arch Otorhinolaryngol 2018; 275(1): 169-79. https://doi:10.1007/s00405-017-4760-z